Animal & Dairy Sciences

Auburn University

ANSC 362
Repro-Tech Update - 9

Genzyme Transgenics Announces
First Successful Cloning of Goats

Press Release of April 26, 1999
Also See:  Nature Biotechnology May 1999, P.456


April 26, 1999 / FRAMINGHAM, Mass./  -- Genzyme Transgenics Corporation (Nasdaq: GZTC), Louisiana State University and Tufts University School of Veterinary Medicine announced in the May issue of Nature Biotechnology that collaborating scientists from these organizations produced the world's first cloned transgenic  goats. The three healthy, identical females were born in October and November 1998 at Genzyme Transgenics' farm in central Massachusetts. The first cloned transgenic goat produces human antithrombin III (rhATIII) in its milk. Transgenics is the process of taking DNA from one species and implanting it into the genetic structure of another. Genzyme Transgenics uses this process in the development and production of human therapeutics in the milk of animals. "Antithrombin III is the first transgenically produced protein to be introduced in human clinical trials and progress to Phase III testing," said Sandra Nusinoff Lehrman, M.D., president and chief executive officer of Genzyme Transgenics Corporation. "This successful cloning effort advances our mission to efficiently produce transgenic biopharmaceuticals with the potential to treat a variety of important medical illnesses and diseases."



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