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Sandra J. Ewald is a native of Texas and is a Professor in the Department of Poultry Science with a joint appointment in the Department of Pathobiology. Her teaching responsibilities include a graduate level course taught through the Veterinary Biomedical Sciences program. She is a member of the American Association of Immunologists, and the NE-60 Multistate Research Project (Genetic Bases for Resistance and Immunity to Avian Diseases).

EDUCATION:

1976 to 1979 - Postdoctoral Fellow at California Institute of Technology
1976 - Ph.D., Zoology (Immunogenetics), University of Texas
1970 - B.A., Biology, University of Texas

RESEARCH:

Recent studies focus on molecular characterization of genes of the chicken major histocompatibility complex (MHC). The MHC influences resistance to a number of infectious diseases in chickens. We are presently examining immunological mechanisms of resistance to disease.

SELECTED SCIENTIFIC PUBLICATIONS:

Livant, E.J., D. Zheng, L.W. Johnson, W. Shi and S.J. Ewald. 2001. Three new MHC haplotypes in broiler breeder chickens. Animal Genetics 32:123-131.

Zheng, D., O'Keefe, G., Li, L., Johnson, L.W., and Ewald, S.J. 1999. A PCR method for typing B-LBII family (class II MHC) alleles in broiler chickens. Animal Genetics 30:109-119.

Li, L., Johnson, L.W., Livant, E.J., and Ewald, S.J. 1999. The MHC of a broiler chicken line: Serology, B-G genotypes, and B-F/B-LB Sequences. Immunogenetics 49:215-224.

Livant, E.J., Welles, E.G., and Ewald, S.J. 1997. Chronic ethanol exposure alters leukocyte subsets in repopulating spleens but does not alter negative selection in thymuses of sublethally irradiated mice. Alcohol. Clin. Exp. Res. 21:1520-1529.

Li, L., Johnson, L.W., and Ewald, S.J. 1997. Molecular characterization of major histocompatibility (B) haplotypes in broiler chickens. Animal Genetics 28:258-267.

Ewald, S.J., Lien, Y.-Y., Li, L., and Johnson, L. W. 1996. B-haplotype control of CD4/CD8 subsets and TCR VB usage in chicken T lymphocytes. Vet. Immunol. Immunopathol. 53:285-301.

STAFF PHOTOS:

Emily J. Livant
Research Fellow II
livanej@vetmed.auburn.edu

LABORATORY CAPABILITIES:
Serological typing for broiler B blood groups (MHC haplotypes); PCR typing of MHC haplotypes; molecular cloning; flow cytometry.