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Channel catfish virus CCV is an important fish virus causing economic losses in areas where
 . channel catfish Ictalurus punctatus is cultured. Although it has been almost three decade since
the virus was isolated, molecular studies on CCV lagged behind other herpesviruses. Earlier
studies dealt mostly with the basic biologic properties of CCV, and most of these studies focused
on the pathogenecity and the detection strategies of the disease. Availability of the DNA sequence
of CCV prompted many laboratories to study unique molecular characteristics of CCV to find its
place in herpesvirus classification. The genomic structure of CCV was different enough so that
CCV was given its own place within the herpesvirus classification. Unfortunately, some of the
most important common characteristics of herpesviruses, such as gene regulation, latency, and
virus