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Nannan Liu

Associate Professor


Dept. of Entomology and Plant Pathology
Cellular and Molecular Biosciences Program (AU-CMB)
Auburn University, Alabama, 36849

Tel: (334) 844-2661
Fax: (334) 844-5005
E-mail: liunann@auburn.edu

Education:

1990-1995         Ph.D. Insect Molecular Toxicology, Cornell University, Ithaca, NY. 

1978-1982         B.S. Biology, China Agriculture University, Beijing, China.

 

Professional Experience:

2003-Present        Associate Professor, Insect Molecular Toxicology and Physiology, Department of Entomology and Plant Pathology, Auburn University. 

1997-2002           Assistant Professor (68% research, 32% teaching), Insect Molecular Toxicology, Physiology. Department of Entomology and Plant Pathology, Auburn University. Molecular toxicology and physiology relating to mechanisms of insecticide resistance in                                      mosquitoes, house flies, and German cockroaches; functional genomics of insect polyphenisms and development.

1996-1997           Postdoctoral Research Associate, Department of Entomology, Cornell University (with Dr. Jeffrey G. Scott). Regulation of cytochrome P450 (CYP6D1) gene expression in insecticide resistance of house flies. 

1995-1996           Postdoctoral Fellow, Department of Biochemistry and Biophysics, University of Rochester, School of Medicine and Dentistry (with Dr. Mahin D. Maines). Heme oxygenase gene regulation in rats. 


1990-1995           Graduate Research Associate, Department of Entomology, Cornell University (with Dr. Jeffrey G. Scott). Mechanisms of resistance and molecular genetics of monooxygenase-mediated resistance in house flies. 

 

Research:
 

My research goals are to conduct research on: (1) the physiological and molecular mechanisms involved in insecticide resistance of medically important insects, including mosquitoes, house flies, and German cockroaches; (2) the molecular basis of gene regulation; (3) functional analysis of the genes involved in resistance and genetic manipulation of resistance genes; and (4) genes and their physiological functions in insect development, reproduction, and polyphenisms. The overall goal of my research is to improve management of medically and agriculturally important insects.

 

Teaching:

ENTM 7100 (Toxicology)

ENTM 7200 (Insect Physiology)

 

Graduate Students

Qiang Xu, Ph.D., 2003-present.The research is focused on the mechanisms of insecticide resistance inmosquitoes.

Fang Zhu, Ph.D., 2003-present. The research is focused on detoxification mediated resistance in house flies.

Ting Li, M.S., 2007-present. The research is focused on insecticide resistance in Mosquitoes.

 

Professional Memberships:

Entomological Society of America

American Association for the Advancement of Science

American Chemical Society

 

Publications

Peer-Reviewed and Refereed Articles since 2000 ( *Indicates the Author for Correspondence)

 

  1. *Liu, N., H. Liu, F. Zhu and L. Zhang. 2007. Differential Expression of Genes in Pyrethroid Resistant and Susceptible Mosquitoes, Culex quinquefasciatus (S.). Gene 394, 61-68.
  2. *Liu, N., Q. Xu and L. Zhang. 2006. Sodium Channel Gene Expression in Mosquitoes, Aedes albopictus (S.) Insect Sci. 13, 431-436.
  3. Xu, Q., H. Wang, L. Zhang and N. Liu*. 2006. Posttranscriptional regulation of sodium channel gene expression in insecticide resistance. Gene 379, 62-67.
  4. *Liu, N., Q. Xu, F. Zhu and L. Zhang. 2006. Pyrethroid resistance in mosquitoes. Insect Sci. 13, 159-166.
  5. Xu, Q., H. Wang, L. Zhang and N. Liu*. 2006. Kdr allelic expression of the sodium channel gene in insecticide resistance of Culex quinquefasciatus. Biochem. Biophys. Res. Com. 345, 774-780.
  6. *Liu, N., F. Zhu, Q. Xu, J. W. Pridgeon and L. Zhang. 2006. Behavioral change, physiological modification, and metabolic detoxification: mechanisms of insecticide resistance. Acta Entomologica Sinica 48, 672-680.
  7.  Lee, S. E., B. C. Campbell, Y. S. Ok, J. H. Kim, B. S. Park and N. Liu. 2005. Biochemical changes in dehydrogenase, hydroxylase and tyrosinase of a permethrin-resistant strain of housefly larvae, Musca domestica L. Environ. Toxicol. Pharmacol. 20, 258-263.
  8. Liu, H., Q. Xu, L. Zhang and N. Liu*. 2005. Chlorpyrifos resistance in the mosquito Culex quinquefasciatus. J. Med. Entomol. 42, 815-820.
  9. Xu, Q., H. Liu, L. Zhang and N. Liu*. 2005. Resistance in the mosquito, Culex quinquefasciatus, and possible mechanisms for resistance. Pest Manag. Sci. 61, 1096-1102.
  10. *Liu, N. and L. Zhang. 2004. CYP4AB1, CYP4AS1 and Gp-9 overexpression in workers of the red imported fire ant, Solenopsis invicta. Gene 327, 81-87.
  11.  Liu, H., E. W. Cupp, K. M. Micher, A. Guo and N. Liu*. 2004. Insecticide resistance and cross-resistance in Alabama and Florida strains of Culex quinquefaciatus (S.). J. Med. Entomol. 41, 408-413.
  12. *Liu, N., J. W. Pridgeon, H. Wang, Z. Liu and L. Zhang. 2004. Identification of the mariner transposable element from house flies and German cockroaches. Insect Mol. Biol. 13, 443-447.
  13. Liu, H., E. W. Cupp, A. Guo and N. Liu*. 2004. Insecticide resistance in Aedes albopictus (S.). J. Med. Entomol. 41, 946 - 952. 
  14. Pridgeon, J. W., L. Zhang and N. Liu*. 2003. Overexpression of CYP4G19 associated with pyrethroid resistant German cockroaches. Gene 314, 157-163.
  15. Pridgeon, J. W. and N. Liu*. 2003. Overexpression of the cytochrome c oxidase subunit I gene associated with a pyrethroid resistant strain of German cockroaches, Blattella germanica. Insect Biochem. Mol. Biol. 33, 1043-1048.
  16.  *Liu, N. and L. Zhang. 2002. Identification of two cytochrome P450 genes and their 5’ flanking regions from the house fly, Musca domestica (L.). Insect Biochem. Mol. Biol. 32, 755-764.
  17. *Liu, N. and J. W. Pridgeon. 2002. Metabolic detoxication and the kdr mutation in pyrethroid resistant house flies, Musca domestica  (L.). Pestic. Biochem. Physiol. 73, 157-163.
  18. Pridgeon, J. W., A. G. Appel, W. J. Moar and N. Liu*. 2002. Variability of resistance mechanisms in three strains of pyrethroid resistant German cockroach, Blattella germanica (L.). Pestic. Biochem. Physiol. 73, 149-156.
  19. *Liu, N. and X. Yue. 2001. Genetics of pyrethroid resistance in the house fly (Diptera: Muscidae).  Pestic. Biochem. Physiol. 70, 151-158.
  20. Wei, Y., A. Appel, W. J. Moar and N. Liu*. 2001. Pyrethroid resistance and mechanisms in the German cockroach, Blattella germanica (L.). Pest Manag. Sci. 57, 1055-1059.
  21. *Liu, N. and X. Yue. 2000. Insecticide resistance and cross-resistance in the house fly (Diptera: Muscidae). J. Econ. Entomol. 93, 1269-1275.
  22. Liu, N., X. J. Wang, W. K. McCoubrey and M. D. Maines. 2000. Developmentally regulated expression of two transcripts for heme oxygenase-2 with a first exon unique to rat testis: control by corticosterone of the oxygenase protein expression. Gene 241, 175-183.